ea0014p431 | (1) | ECE2007
Dubois Séverine
, Illouz Fréderic
, Laboureau Sandrine
, Draunet Catherine
, Rohmer Vincent
, Guichet Agnès
Within the group of gonosomal aneuploidy, the 47,XXY Klinefelter syndrome is a well-known chromosomal anomaly with a clearly delineated phenotype. Since the 48,XXYY polysomy is rather rare and associated with hypogenitalism, it has often been considered as a variant of the Klinefelter syndrome. Nevertheless, several differences have been reported, in particular the greater severity and prevalence of mental retardation and psychiatric illness in patients with a 48,XXYY syndrome...